Tom Lipton, OxTools, did a video on cutting metric threads on an imperial lathe. The problem with not being able disengage the half nuts due to losing synchronization is that you have to be able to stop the lathe quickly enough to avoid running past the gutter. For lathes with a VFD and dynamic braking,it isn't that big an issue but for a lathe with an induction motor, stopping when the you hit the gutter but avoiding running into a shoulder can be tense.
However, if you disengage the half nuts and shut the lathe down, then reverse the lathe and reengage the half nuts when the same number on the thread dial hits the index mark, you will not lose synchronization. You still have to run the lathe in reverse to the starting point but it eliminates the butt clenching for metric threading.