How many threads are on the back of the spindle? You really only need about four threads. My 10x22 has two nuts on the spindle. I removed one of them and screwed on my spider in its place. The nut is about 4 or 5 threads thick. The spindle is unaltered.
Well, I've done a few other things to my lathe, but I haven't touched the spindle at all. (Improved compound clamp, set true back plate, DRO and home made ELS.)