Using a tapped hole through all of your "made by you" reducing bushings instead of a drill-through hole would work I suppose but (a) it would be a lot of extra work for zero gain and (b) assuming that the thread start would have to match the thread finish in the holder within one degree, the odds are 360:1 against you ever finding another cutter holder that those bushings would work with. So if you use a hole instead of a slot, use a drill-through hole, not a threaded one.