Some good replies here
@gi_984.
I have built two homes and two shops from the ground up in the last 14 years or so. So much of it is personal preference but judging by your initial description, you will have a setup similar to mine, whereas the shop has the exact same look as the house.
One of the big decisions you will need to make is which concrete contractor to use. I was fortunate that I had a crew that was beyond fantastic. The floors in both the house and shop are unbelievably flat and smooth. No worries about having a flat foundation for that first sill plate.
I love natural light and have quite a few windows in my shop. I get to watch the wildlife in my wooded acreage or the doggies playing in the yard. I could live in fear of break-ins, but I will not have potential thieves dictate how I will live. They might have to answer to "Ruger."
For the electrical, do as others have mentioned here and put in a large panel. I had to add a subpanel to mine already. Keep in mind that every 220v outlet is 2 panel slots. I have seven 220s and therefore lost 14 panel slots right off of the bat.
Insulate well, although you are in what I would call a moderate climate. Install a mini-split for heating and cooling.
Bathroom with sink and stool - yes. You will not regret it, and neither will the wife when you need to clean up before coming into the house.
I have 11ft ceilings in mine. It allows one to have ceiling fans and move material around without clipping the ceiling.
LED strip lights. 50lm/sq ft minimum. I would recommend more.
I have finished 5/8" plywood on my walls. It allows me to hang pretty much anything anywhere without finding a stud. The bottom 40" or so is a metal wainscot. Looks good and keeps any sparks away from the wood structure.
I hope you don't mind a couple of pictures showing the house and matching shop. My shop is 36x36 (and waaaay too small, LOL).