Holding by the centre hole is fine for drilling, not for milling. It's one of those things you'll get away with until you don't, then it's quite catastrophic!
By fixture plate, I mean some arrangement to hold or otherwise interface between the work and the table in such a way that allows access for the machining ops you want to carry out. A large flat plate with holes drilled strategically will probably do. You've picked quite a challenging project for first time with an RT, it has to be said!
When workholding on my RT I do often use the center hole, with at least two other points of clamping, moving clamps if needed for clearance. Order of operation is critical.