FWIW, I’m going to veer back to screwless vises (see thread topic) and touch on why I have one on an LMS 5500 that I mentioned earlier. I struggled with the vise overhang issue before I settled on a Tormach 90mm screwless vise and so far I have no regrets. One advantage of a screwless vise or a “CNC” vise is they aren’t restrained to certain locations on the table by having to line up hold down bolt slots with slots in the table. Mine is mounted flush with the back of the mill table with hold down clamps, so it eats up no Y travel. But, I can see where that might not be a concern if one had an X-axis DRO mounted to the back of the table. A little overhang wouldn’t matter. It also may or may not be a concern on the new LMS 5550 since its larger table reduces Y travel by over an inch compared to my 5500 anyway.
I've enjoyed my 3" screwless vise for years, but to go back to the original theme of this thread, I can't get mine to tighten correctly on workpieces these days, despite cleaning it out, backing it off etc. Maybe it's just getting tired.