"Excessive" is a tough term to define.
All gears wear. Even super-duper tough and hardened ones wear. And when they need replaced, they're often accused of 'excessive wear'. Indeed, that's exactly the reason they get replaced! So it's a matter of how much and how long.
They will wear *differently*. That much is true. And you'll have to examine relative sizes and therefore loads. For instance, a small pinion meshed with a large gear will have a likelihood of tearing up teeth if the gears are of dissimilar hardness and toughness. But QCGB gears don't see high loads in the first place (hence, the Zamak). Even Nylon would work (and run a lot quieter ;-). But once you switch materials, all you really get is a different wear pattern. Whether that's up to your standard or not is another issue.
That bit of trivia aside, surely someone has done this and has a success/failure story to share.
Wrat