Have you done this? Is that an actual problem or just something to be aware of?
I'm just a professional engineer (mechanical) with 30+ years of design/manufacturing/commissioning experience with industrial machinery that used hydraulic and AC servos for some applications.
And I've been crunching the numbers for my own conversion.
So I plugged some numbers into my model.
Suffice to say, a 6mm thick x 100mm OD aluminum disc at motor speed has as almost 8X the inertia as a 100kg mass load driven with a 5mm pitch screw.
And a little over 3 times the inertia of the Nema23 motor I have in my spreadsheet.
It effectively doubles the inertia of the whole Nema23 system as I have it modeled.
The reality is, while machining, it will likely never be an issue. But it will definitely become a limiting factor when you try to go faster with a stepper system, and you don't know when you've lost a step or two.
It's easy enough to remove the handles, and basically enable double the acceleration potential.
BTW, Mr. Dawson with his DC servos and direct reading closed loop feed-back has a real industrial control system on his machine, not the hobby grade toy stuff we are playing with here. To replace his stuff with new industrial gear, you are likely talking north of 10k per axis, and that's without the CNC software.