I have a room that has OSB on walls and ceiling and floor. ...I will be welding in this area and am concerned about burning the place down
Such concern indicates... good mental health.
There are ire-retardant paints that instead of burning kind of 'puff up' when hot (and this insulates the wood behind them).
OSB is very thirsty, you'll want to spray on some primer first (the 'contains shellac' kind dries in an hour or three) and then
follow up with a suitable fire-retardant paint. Any good paint store will have some options.
Both brush and roller are annoyingly ineffective on OSB; you really need a sprayer, and priming first is key to keeping paint
usage modest.
That's good for walls, but for a ceiling I'd go with sheetrock (could be thin stuff); it's relatively easy to apply with glue/screws
and a helper or two with T-shaped sticks can hold the panels up while you apply the screwgun. Tape/mud on the seams
is always an option, but few folk will notice ceiling appearance.
As for the floor... no idea. You might not want to seal it (depends on moisture from below) and paint won't hold up.
If you don't have concrete, or dirt, it won't take hot falling objects gracefully. I'd be tempted to use lots of
cheap ceramic tiles, and just let 'em break from time to time... that's gonna be time-consuming, though.