I'm sort of a welder geek and have owned literally dozens of Millermatic machines and most of the spool guns....Spoolmatic 1, Spoolmatic 3, Spoolmate 200, Spoolmatic 30A and they all work really nicely. They take some dialing in to get a feel for the wire speed and voltage combination, but it's not difficult. I think it took me about five minutes to get an acceptable bead the first time I ran one. The only real downside is that they only take the small spools of wire.
Both the 252 and 255 will take a push/pull gun, which may be an option for you. The push-pull guns cost more, but for some things are better. The push/pull guns from Miller are a bit bulkier than the spool guns, but allow you to run a large diameter spool on the machine. You use U-shaped rollers in the machine's drive and there is a motor in the gun that pulls the wire. You adjust the push side on the machine to match up with the push-pull gun. The push-pull gun will be marked with a setting you put into the welder so the two are in sync...usually that's all it takes, but it can be tweaked if necessary. The other nice thing with the push-pull setup is that (at least on my 350P) when you adjust the wire speed at the gun end it shows in the wire speed display on the machine so you're not guessing what the wire speed is. On the Spoolmatic 30A it simply has a dial 1-10 that doesn't correlate directly to wire speed. I never ran a push-pull gun on my 252, but I would expect it and the 255 show wire speed on the machine as well. The push-pull guns do cost more than the spool guns, but nothing blue is cheap these days!
It seems like the folks doing heavier aluminum projects seem to go with the push-pull setup largely because of the big spool of wire. I've read about guys in the pacific northwest and Alaska who make aluminum boats and many of them say the push-pull setup is the only way to go. I've heard some of them will keep a spool gun handy for tighter spots, but that's probably overkill for most of us hobby welders.
What sort of projects are you planning? I think that would really dictate it more than anything else. If money is no object, just get a 350P Aluminum and be done with it...but it really is only for aluminum. The standard 350P with the push-pull gun is a close second and what I'm using now...really amazing machine.