This can also happen if your leadscrew or drivescrew are bent. As they spin, they put an uneven force on the carriage through the apron and if the carriage gibs are too loose, the movement shows-up in the workpiece. Check everything in the carriage drive train, clean the acme screw, check the thrust bearings ( as suggested below) etc. If your ways are worn badly, the problem might not be correctable.
Ray