One is a standard numerical display vs the other is a LCD (graphical display), also the MX200L is a touch screen and has soft keys as opposed to fixed push buttons on the MX100L. Personally I find the graphical displays to be much easier on the eyes, and work better if you have sunny/shade on the display. Downside of the touch keypads is they work less optimally with greasy/wet fingers. I have the EL700 which is the previous version of the EL750 which is the same as the MX200L, I put a protective touch screen over the whole display. You can buy them for different touch pads, and put them to fit the display, less worry of damaging the display and easily replaceable. There is also a less expensive graphical display with glass scales. Lathe DRO for 2 axis is quite basic, often do not use a lot of the other DRO features. Also, DRO's with soft keys can be programmed for different types of machines and the soft keys (typically on the bottom under the screen) will change functions depending on the machine specified.