If you can, a "project box" from one of the many manufacturers would be a lot cheaper than a block of delrin that you turn 90% of into chips. There's nothing wrong with cutting one though, and I can't see any reason it wouldn't work.
Depending on the electronics, you might also be able to use an external antenna. I've got a wifi connected device outside now in an aluminum box with an external antenna that works great.
I hear you. It does seem a waste, but using a "standard" plastic box means there's additional fab work like making stand offs, adapting to the internal features of the box, all on a box that may not have square parallel sides. (So they can get it out of the mold.)
The board I have uses a soldered on module with an integral PCB antenna, so no option for an external antenna.
A quick check on Newark and Aliexpress show some boxes that have interfering features where I don't want them, or they are not the right size. The Polycase look interesting, but the standoffs are in a place that would require making an adapter plate. Fortunately that isn't hard. If I am understanding the drawing for SN27C-01 correctly, the locking tabs are all on the long side, which is good. The price is right, which makes it worth thinking about a little further. It wasn't what I was envisioning, but maybe there's need to envision something different. I would have to mill out a slot for the power cord and some connectors on the short ends. The 3 degree mold release angle of the cover will make it hard to hold. Since I'd be cutting out the cover for the display, I guess I could screw down the cover to a plate and machine the cover slots on the mill table. After that, I'm not sure how I'd mill out a rectangular hole in the cover. Might have to make little hold downs as I go, without losing the position.
By milling it out of the block, the standoffs are integral to the design and are not wobbly nor questionably anchored nor are there holes through the box. There would be some meat in the cover to attach a bezel, if I designed it correctly.
I've not had the best experience adapting some boxes, but to be fair, those experiences were before having a mill and precise positioning ability. That should make things a lot easier. It can be hard to adapt something that just wasn't designed with your needs in mind. Other times you get lucky. It isn't really luck, but simply one's experience base was larger, or you simply have practiced more...