Safest way is to always drop it in at the same number you started, if you want to experiment make a light cut, check your pitch, drop it in on different numbers with the cross slide backed off, stop the machine and wind the cross slide in to see if things line up, remember to disengage the split nut and wind the cross slide out before restarting, you can aways just leave the split nut engaged and just go from forward to reverse through the whole threading process.